Abstract A general chemical phosphorylation method based on P (III) chemistry has been developed. The system is demonstrated for the phosphorylation of oligonucleotides, directly after their synthesis on a solid support, and for the O-phosphorylation of serine, threonine, and tyrosine as well as for a serine-containing peptide.
[Imoto, Shuhei; Patro, Jennifer N.; Jiang, Yu Lin; Oka, Natsuhisa; Greenberg, Marc M. Journal of the American Chemical Society, 2006 , vol. 128, # 45 p. 14606 - 14611]