Peptides

Design, synthesis and biological activity of peptidomimetic analogs of insect allatostatins

…, ZP Kai, SS Tobe, X Le Deng, Y Ling, XQ Wu, J Huang…

文献索引：Xie, Yong; Kai, Zhen Peng; Tobe, Stephen S.; Deng, Xi Le; Ling, Yun; Wu, Xiao Qin; Huang, Juan; Zhang, Li; Yang, Xin Ling Peptides, 2011 , vol. 32, # 3 p. 581 - 586

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被引用次数: 12

摘要

Allatostatins (ASTs) comprise a family of insect neuropeptides isolated from cockroaches and found to inhibit the production of juvenile hormone (JH) by the corpora allata (CA). For this reason, the ASTs can be regarded as possible IGR candidates for pest control. Six peptidomimetic analogs according to the C-terminal pentapeptide of ASTs were prepared by solid-phase organic synthetic methods in an attempt to obtain new simple substitution ...