Abstract 3-Amino-5-methyl-4, 5-dihydroisoxazole (1) was obtained from N-hydroxyurea and crotononitrile or allyl cyanide in alkaline solution. Use of hydroxylamine, however, gave only low yields of 1. Attempts on an preparative scale to dehydrogenate 1 to 3-amino-5- methylisoxazole (2) failed with the free compound as well as with its benzenesulfonamide derivatives. The 3-aminoisoxazoles 2, 7, 9 and 12 were found to be accessible without ...
