Tetrahedron letters

A novel method for cyclopentanone annulation. The use of 1-(2-ketoalkyl) cyclopropanols to obtain cyclopentanones.

JT Carey, P Helquist

文献索引：Carey, James T.; Helquist, Paul Tetrahedron Letters, 1988 , vol. 29, # 11 p. 1243 - 1246

全文：HTML全文

被引用次数: 13

摘要

Abstract The condensation of alkyl-substituted thermodynamic enolates with ethyl bromomagnesium cyclopropanone hemiacetal (a cyclopropanone equivalent) provides 1-(2- ketoalkyl) cyclopropanols which in turn are converted into 3-hydroxycyclopentanones by treatment with base.