Potent inhibitory effects of N-aryl S-alkylthiocarbamate derivatives on the dopa oxidase activity of mushroom tyrosinase
KH Lee, M Koketsu, SY Choi, KJ Lee, P Lee…
文献索引：Lee, Kun Ho; Koketsu, Mamoru; Choi, Sang Yoon; Lee, Kang Jin; Lee, Pyeongjae; Ishihara, Hideharu; Kim, Sun Yeou Chemical and Pharmaceutical Bulletin, 2005 , vol. 53, # 7 p. 747 - 749
This study reports the potent inhibitory effect of N-aryl S-alkylthiocarbamate derivatives on mushroom tyrosinase (MT) activity. N-Aryl S-alkylthiocarbamate derivatives were found to exhibit a potent inhibitory effect on the dopa (3, 4-dihydroxyphenylalanine) oxidase activity of mushroom tyrosinase. Most of the N-aryl S-alkylthiocarbamate derivatives (compounds from A to J) exhibited higher inhibitory effects than kojic acid (IC 50= 318 μm), a well ...
