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Synlett

Synthetic Study on Ecteinascidin 743 Starting from D-Glucose

A Endo, T Kann, T Fukuyama

文献索引:Endo, Atsushi; Kann, Toshiyuki; Fukuyama, Tohru Synlett, 1999 , # 7 p. 1103 - 1105

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被引用次数: 19

摘要

Abstract: During the course of synthetic study on ecteinascidin 743 (1), key intermediate 5 was prepared. Stereocontrolled synthesis of 5 from D-glucose was accomplished using incorporation of two nitrogen atoms and stereoselective addition of a phenol to an imine as key steps. Key words: ecteinascidin 743, D-glucose, bicyclo [3.3. 1] system, imine