Abstract Some sulfur analogs of 2-dialkylaminomethyl-1, 4-benzo-dioxans were synthesized and evaluated as aL-adrenergic blocking agents to observe the effect of substitution of sulfur for oxygen on adrenolytic activity. Reaction of 2-hydroxybenzenethiol with dialkyl-2, 3- dibromopropylamines resulted in the formation of 2-dialkylaminotnethyl-1, 4-benzoxathians. The structure of these compounds was proven by the use of NMR spectroscopy. In an ...
