Abstract To find out whether the 1, 4-addition to 1, 2: 3, 4-diepoxides, which so far has been observed only once, is of a more general character, we investigated the reaction of a variety of O-, C-, N-, and S-nucleophiles with the model compound 1, 2: 3, 4-diepoxy-2, 3- dimethylbutane (Scheme 4). In several cases, 1, 4-addition products could, indeed, be observed besides the expected 1, 2-adducts (Table).
