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Il Farmaco

EVALUATION OF ANTIINFLAMMATORY AND ANALGESIC PROPERTIES. II.

…, P MASSARELLI, L CHIASSERINI, C PELLERANO

文献索引:Savini; Massarelli; Chiasserini; Pellerano; Bruni Farmaco, 1994 , vol. 49, # 10 p. 633 - 639

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被引用次数: 16

摘要

Summary–Several 1-[quinolyl (4)]-1, 2, 3-triazoles were synthesized by 1, 3-dipolar cycloaddition of 4-azidoquinolines with activated methylene compounds, The synthesized compounds, tested for antiinflammatory and analgesic activities, resulted moderately active as antiinflammatories, but with a very interesting analgesic activity, sometimes higher than that of indomethacin, used as reference drug. Some of the triazole derivatives were ...