N-Fluoro-3-ethyl-3-methyl-1, 1-dioxo-2, 3-dihydro-1H-1λ 6-benzo [e] 1, 2-thiazin-4-one, a new and efficient agent for electrophilic fluorination of carbanions
Y Takeuchi, Z Liu, E Suzuki, N Shibata…
文献索引：Takeuchi, Yoshio; Liu, Zhaopeng; Suzuki, Emiko; Shibata, Norio; Kirk, Kenneth L. Journal of Fluorine Chemistry, 1999 , vol. 97, # 1-2 p. 65 - 67
N-Fluoro-3-ethyl-3-methyl-1, 1-dioxo-2, 3-dihydro-1H-1λ6-benzo [e] 1, 2-thiazin-4-one (1) was prepared in good yield by fluorination of the corresponding sultam (3) with FClO3. The sultam (3) was prepared from saccharin (2) in 3 steps. The N-fluorosultam (1), a very stable crystalline solid, was found to fluorinate carbanions readily in good to excellent yields.
