Discovery of AZD6642, an inhibitor of 5-lipoxygenase activating protein (FLAP) for the treatment of inflammatory diseases

M Lemurell, J Ulander, S Winiwarter…

文献索引：Nowak-Wydra, Barbara; Gierczyk, Blazej; Schroeder, Grzegorz Magnetic Resonance in Chemistry, 2003 , vol. 41, # 9 p. 689 - 692

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被引用次数: 9

摘要

... Volume: Page: ... the identification of a novel scaffold that significantly shifted the molecular property space of the chemical series and ... Chemistry The strategy during the lead generation phase was to simplify the synthesis of screening compounds by designing ...