Abstract A series of pseudonucleoside analogs has been prepared from the base-catalyzed condensation of methyl 3, 3-dimelhoxy-2-(telrahydrofuran-2-yl) propionate with urea and thiourea, followed by cyclization (s) with acid, bromine and peroxyformic acid. Some of their reactions which lead to other model pseudonucleosides are reported.