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Journal of medicinal chemistry

2-Benzyl-and 2-Phenyl-3, 4-dihydroxyphenyl-alanine1

A Burger, WE Coyne, G Janssen

文献索引:Burger,A.B. et al. Journal of Medicinal Chemistry, 1963 , vol. 6, p. 614 - 616

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被引用次数: 5

摘要

solution-of 0.4 g.(17.5 mmoles) of sddium in 40 ml. of absolute ethanol were added 3.8 g.(17.5 mmoles) of diethyl acetamidomalonate and crude 2-phenylveratryl chloride [prepared from 5.35 g.(2.5 mmoles'i of 3-phenj lveratrole]. Bfter 9 hr. of refluxing and stirring, the precipitated sodium chloride was filtered and the filtrate evaporated under reduced pressure. The residue was dissolved in ether and the ether solution was washed with ...