Analytical biochemistry

Synthesis and characterization of cis-4-decenoyl-CoA, 3-phenylpropionyl-CoA, and 2, 6-dimethylheptanoyl-CoA

HF Sobhi, PE Minkler, CL Hoppel

文献索引：Sobhi, Hany F.; Minkler, Paul E.; Hoppel, Charles L. Analytical Biochemistry, 2010 , vol. 401, # 1 p. 114 - 124

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被引用次数: 2

摘要

The measurement of acyl-CoA dehydrogenase activities is an essential part of the investigation of patients with suspected defects in fatty acid oxidation. Multiple methods are available for the synthesis of the substrates used for measuring acyl-CoA dehydrogenase activities; however, the yields are low and the products are used without purification. In addition, the reported characterization of acyl-CoAs focuses on the CoA moiety, not on the ...