前往化源商城

On-resin click-glycoconjugation of peptoids

AS Norgren, C Budke, Z Majer, C Heggemann…

文献索引:Norgren, Anna S.; Budke, Carsten; Majer, Zsuzsa; Heggemann, Carolin; Koop, Thomas; Sewald, Norbert Synthesis, 2009 , # 3 p. 488 - 494

全文:HTML全文

被引用次数: 28

摘要

Abstract Peptoids are unnatural peptide-like oligomers having the side-chain attached to the glycine nitrogen. In order to investigate how such oligomers are affected upon glycoconjugation, a series of glycosylated peptoids has been synthesized. The conjugation between glycosyl residue and peptoid was achieved by azide+ alkyne [3+ 2] cycloaddition (click reaction). The glycosylated peptoids were obtained by either stepwise assembly ...