Anti-HIV activity of stilbene-related heterocyclic compounds

…, AE García-Cadenas, S Sánchez-Palomino…

文献索引：Bedoya, Luis M.; del Olmo, Esther; Sancho, Rocio; Barboza, Bianca; Beltran, Manuela; Garcia-Cadenas, Ana E.; Sanchez-Palomino, Sonsoles; Lopez-Perez, Jose L.; Munoz, Eduardo; Feliciano, Arturo San; Alcami, Jose Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 15 p. 4075 - 4079

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被引用次数: 32

摘要

Viral transcription has not been routinely targeted in the development of new antiviral drugs. This crucial step of the viral cycle depends on the concerted action of cellular and viral proteins such as NF-κB and Tat. In the present study, stilbene-related heterocyclic compounds including benzalphthalide, phthalazinone, imidazoindole and pyrimidoisoindole derivatives are tested for their anti-HIV activity. Original assays based on recombinant ...