Chemical and Pharmaceutical Bulletin

β-Arylaminoacrolein Derivatives. I. The Investigation of Combes Reaction and the Syntheses of β-Arylaminoacrolein Derivatives as the Possible Reactant

S TAMURA, E YABE

文献索引：Tamura; Yabe Chemical and Pharmaceutical Bulletin, 1973 , vol. 21, # 10 p. 2105 - 2111

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被引用次数: 21

摘要

The limitations of Combes reaction were reinvestigated. 4-(p-Chloroanilino)-3-penten-2-one (III), hitherto believed to be insusceptible to cyclodehydration in sulfuric acid, reacted at a higher temperature to give 2, 4-dimethyl-6-chloroquinoline (IV). 4-Anilino-3-buten-2-one (V),