The Journal of organic chemistry

Au (III)/TPPMS-Catalyzed Benzylation of Indoles with Benzylic Alcohols in Water

H Hikawa, H Suzuki, I Azumaya

文献索引：Hikawa, Hidemasa; Suzuki, Hideharu; Azumaya, Isao Journal of Organic Chemistry, 2013 , vol. 78, # 23 p. 12128 - 12135

全文：HTML全文

被引用次数: 21

摘要

A novel and efficient method for the Au (III)/TPPMS-catalyzed direct substitution reaction of benzhydryl and benzylic alcohols with indoles in water is developed. Au (III)/TPPMS is an effective catalyst for the benzylation of the strong π nucleophile 1-methylindole, while common Brønsted or Lewis acids are ineffective.