Synlett

Simple, facile and highly selective tetrahydropyranylation of alcohols using silica chloride

N Ravindranath, C Ramesh, B Das

文献索引：Ravindranath; Ramesh; Das Synlett, 2001 , # 11 p. 1777 - 1778

全文：HTML全文

被引用次数: 13

摘要

Abstract: A simple and efficient process for tetrahydropyranylation of alcohols has been developed by reacting with dihydropyran at room temperature in presence of catalytic amount of silica chloride. The process is highly selective for monoprotection of the hydroxyl groups of symmetric diols. Key words: alcohols, tetrahydropyranylation, silica chloride, symmetric diols, monoprotection