Synthesis and microbiological evaluation of novel [N-acetyl-2, 6-diarylpiperidin-4-yl]-5-spiro-4-acetyl-2-(acetylamino)-Δ 2-1, 3, 4-thiadiazolines

S Balasubramanian, C Ramalingan, G Aridoss…

文献索引：Balasubramanian; Ramalingan; Aridoss; Parthiban; Kabilan Medicinal Chemistry Research, 2004 , vol. 13, # 5 p. 297 - 311

全文：HTML全文

被引用次数: 22

摘要

Abstract. Some novel spiropiperidinyl thiadiazolines have been synthesized and their bacterial activity against Streptococcus faecalis, Bacillus subtilis, Escherichia coli, Pseudomonas aeruginosa and Klepsiella pneumoniae and antifungal activity against Cryptococcus neoformans, Candida-6, Candida-51, Aspergillus niger and Aspergillus flavus were evaluated. Compound 23 exhibited potent antibacterial activity in vitro against ...