Angewandte Chemie International Edition

Efficient Oxidative Cyclization of 1, 6??Dienes: A Highly Diastereoselective Entry to Substituted Tetrahydropyrans

S Roth, CBW Stark

文献索引：Roth, Stefanie; Stark, Christian B. W. Angewandte Chemie - International Edition, 2006 , vol. 45, # 37 p. 6218 - 6221

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被引用次数: 30

摘要

(usually within 10min at 08C) and with high selectivity, irrespective of the starting material. Terminal alkenes, which are commonly known to result in diminished yields in the case of 1, 5-dienes,[3] afforded the heterocyclic products in good yields. Even a chiral morpholine derivative was accessible in excellent yield (87%) starting from simple protected diallylamine (Table 1, entry 8). Since a solid-supported terminal oxidant [10] is used, the ...