Studies of the selective O-alkylation and dealkylation of flavonoids. 10. Selective demethylation of 7-hydroxy-3, 5, 8-trimethoxyflavones with anhydrous aluminum …

T Horie, M Tsukayama, Y Kawamura…

文献索引：Horie, Tokunaru; Tsukayama, Masao; Kawamura, Yasuhiko; Seno, Masamichi Journal of Organic Chemistry, 1987 , vol. 52, # 21 p. 4702 - 4709

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被引用次数: 23

摘要

Demethylation of five 7-hydroxy-3, 5, 8-trimethoxyflavones and their acetates with anhydrous aluminum halides in acetonitrile or ether was studied and the following results were found.(1) The demethylation was apparently influenced by both solvents and afforded 5, 7- dihydroxy-3, 8-dimethoxyflavones in acetonitrile and 3, 7-di-hydroxy-5, 8-dimethoxyflavones in ether as main products.(2) The demethylation with 5% w/v anhydrous aluminum ...