Design, synthesis and antiproliferative properties of some new 5-substituted-2-iminobenzimidazole derivatives
AT Mavrova, D Wesselinova, N Vassilev…
文献索引：Mavrova, Anelia Ts.; Wesselinova, Diana; Vassilev, Nikolay; Tsenov, Jordan A. European Journal of Medicinal Chemistry, 2013 , vol. 63, p. 696 - 701
Some new 1, 3, 5-substituted-2, 3-dihydro-2-imino-benzimidazoles were synthesized under solid–liquid phase transfer catalysis conditions using 5-substituted-2-aminobenzimidazoles as precursors in order to assess their cytotoxicity respectively proliferative activity. The structures of the compounds were confirmed by IR, 1H NMR, 13C NMR and elemental analysis. Compounds 9–10, 12 and 16–17 were evaluated for their cytotoxical effect on ...
