The total synthesis of the clerodane diterpene insect antifeedant ajugarin I

SV Ley, NS Simpkins, AJ Whittle

文献索引：Ley, Steven V.; Simpkins, Nigel S.; Whittle, Alan J. Journal of the Chemical Society, Chemical Communications, 1983 , # 9 p. 503 - 505

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被引用次数: 21

摘要

The first total synthesis of the polyoxygenated diterpene insect antifeedant ajugarin I (1) has been achieved by a route which involves a new method for the construction of 3-substituted-A*-butenolides. ... As a result of an observation that Ajuga remota (Labiatae) plants were not eaten by various insect species, subsequent isolation studies afforded three new polyoxygenated clerodane diterpene antifeedants,l the major component being assigned the structure ...