The Journal of organic chemistry

A Practical, Two-Step Synthesis of 2-Substituted 1, 3-Butadienes

S Sen, S Singh, SMN Sieburth

文献索引：Sen, Sushmita; Singh, Swapnil; Sieburth, Scott McN Journal of Organic Chemistry, 2009 , vol. 74, # 7 p. 2884 - 2886

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被引用次数: 8

摘要

One of the fundamental building blocks of organic chemistry is the 1,3-diene.(1) Butadienes substituted at C-2 are a pivotal component of our new method for constructing optically active 3-alkyl-4-silyl -1-butenes, but few 2-alkyl-1,3-butadienes are commercially available.(2) A broad set of methods have been described for preparation of substituted 1,3-dienes;(3, 4) however, a review of these procedures with a goal of generating simple 2-substituted derivatives in multigram ...