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Antimalarial arylaminopropanols

WT Colwell, V Brown, P Christie, J Lange…

文献索引:Colwell,W.T. et al. Journal of Medicinal Chemistry, 1972 , vol. 15, p. 771 - 775

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被引用次数: 40

摘要

A number of aromatic nuclei are associated with significant antimalarial activity when attached to N-alkylaminoethanol or a-piperidylmethanol side chains. A series of N- monoalkyl-and N, N-dialkylaminopropanol side chains have now been attached to a series of these active nuclei. The preparation and antimalarial activity of the aminopropanol variants are described. The antimalarial bioassay data for the title compounds show an ...