Cobalt Catalyzed Functionalization of Unactivated Alkenes: Regioselective Reductive C− C Bond Forming Reactions

B Gaspar, EM Carreira

文献索引：Gaspar, Boris; Carreira, Erick M. Journal of the American Chemical Society, 2009 , vol. 131, # 37 p. 13214 - 13215

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被引用次数: 40

摘要

The cobalt catalyzed hydroaldoximation and hydrocyanooximation of unactivated alkenes is reported. Secondary and tertiary aldoximes and oximonitriles are synthesized with excellent regioselectivity under mild conditions, and conversion of the products to valuable intermediates is documented. The reactions expand the arsenal of reductive carbon− carbon bond forming reactions as well as regioselective functionalizations of unactivated double ...