A Mild and Versatile Method for the Synthesis of Alkyl Ethers from Methoxymethyl Ethers and Application to the Preparation of Sterically Crowded Ethers

Y Minamitsuji, A Kawaguchi, O Kubo…

文献索引：Minamitsuji, Yutaka; Kawaguchi, Atsuhisa; Kubo, Ozora; Ueyama, Yoshifumi; Maegawa, Tomohiro; Fujioka, Hiromichi Advanced Synthesis and Catalysis, 2012 , vol. 354, # 10 p. 1861 - 1866

全文：HTML全文

被引用次数: 5

摘要

Abstract A mild and divergent route for the synthesis of alkyl ethers from methoxymethyl (MOM) and methoxyethyl (ME) ether derivatives via pyridinium-type salt intermediates has been developed. The addition of organocuprates to the salts afforded the corresponding alkyl ethers, including highly crowded ones, in high yields even in the presence of acid-or base-sensitive functional groups.