Glutathione peroxidase-like antioxidant activity of diaryl diselenides: a mechanistic study

…, HB Singh, NS Punekar, RJ Butcher

文献索引：Mugesh; Panda; Singh; Punekar; Butcher Journal of the American Chemical Society, 2001 , vol. 123, # 5 p. 839 - 850

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被引用次数: 263

摘要

The synthesis, structure, and thiol peroxidase-like antioxidant activities of several diaryl diselenides having intramolecularly coordinating amino groups are described. The diselenides derived from enantiomerically pure R-(+)-and S-(-)-N, N-dimethyl (1- ferrocenylethyl) amine show excellent peroxidase activity. To investigate the mechanistic role of various organoselenium intermediates, a detailed in situ characterization of the ...