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Tetrahedron Letters

Electrophilic cyclization of 4-thio-but-2-yn-1-ols via 1, 2-migration of the thio group: efficient synthesis of 2, 4-dihalo-3-thio-substituted furans

H Zhou, J Yao, G Liu

文献索引:Zhou, Hongwei; Yao, Jinzhong; Liu, Guoliang Tetrahedron Letters, 2008 , vol. 49, # 2 p. 226 - 228

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被引用次数: 11

摘要

A facile and efficient method for the synthesis of 2, 4-dihalo-3-thio-furans via the electrophilic cyclization and 1, 2-migration of the thio group of 4-thio-but-2-yn-1-ols was developed. As a result of the ready availability of starting materials and the simple and convenient operation, this synthetic route would have potential utility in organic synthesis.