Synthesis of acyclic and macrocyclic analogs of Di-, Tri-, and tetranucleotides

VE Semenov, VD Akamsin, VS Reznik

文献索引：Semenov; Akamsin; Reznik Russian Journal of General Chemistry, 2007 , vol. 77, # 8 p. 1430 - 1440

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被引用次数: 6

摘要

Abstract Compounds consisting of two or three uracil fragments were synthesized by reaction of methyl-substituted uracil sodium salts with 1-(6-bromohexyl)-3, 6-dimethyluracil or 1, 6-dibromohexane. Treatment of these compounds with paraformaldehyde gave the corresponding pyrimidinophanes and acyclic compounds in which the uracil fragments are linked through methylene bridges. Uracil derivatives having no substituent on N 3 were ...