Synthesis of 6-Methoxy-2-methyl-2-[(1'-methyl-2', 5'-dioxocyclopentyl) methyl]-3, 4-dihydro-naphthalen-1 (2H)-one: Its Novel Base-Catalyzed Rearrangement to a …
DJ Collins, GD Fallon, CE Skene
文献索引：Collins, David J.; Fallon, Gary D.; Skene, Colin E. Australian Journal of Chemistry, 1992 , vol. 45, # 1 p. 71 - 97
Abstract Reaction of 2-dimethylaminomethyl-6-methoxy-3, 4-dihydronaphthalen-1 (2H)-one (7) with 2-methylcyclopentane-1, 3-dione gave 64% of 6-methoxy-2-[(1′-methyl-2′, 5′- dioxocyclopentyl)-methyl]-3, 4-dihydronaphthalen-1 (2H)-one (6a), which with 1 equiv. of ethylene glycol in refluxing benzene in the presence of 4-toluenesulfonic acid yielded a diastereomeric mixture of the 2′, 2̶-ethylenedioxy derivatives (13a, b); the major ...
