Variation in the Site of Lithiation of 2-(2-Methylphenyl) ethanamine Derivatives

K Smith, GA El-Hiti, MB Alshammari

文献索引：Houlden, Chris E.; Lloyd-Jones, Guy C.; Booker-Milburn, Kevin I. Organic Letters, 2010 , vol. 12, # 13 p. 3090 - 3092

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被引用次数: 20

摘要

... regioselectively.(1-4) Lateral (benzylic) lithiation of alkyl groups that are ortho- to a directing metalating group (DMG) is a well-known example of such methodology in organic synthesis.(1a ... products, electrophile, E, yield a (%). ... 12, 4-MeOC 6 H 4 CHO, 4-MeOC 6 H 4 CH( ...