Addition Reactions of Iodomethyllithium to Imines. A Direct and Efficient Synthesis of Aziridines and Enantiopure Amino Aziridines
JM Concellón, H Rodríguez-Solla, C Simal
文献索引:Barluenga, Jose; Llavona, Lujan; Yus, Miguel; Concellon, Jose M. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1991 , # 11 p. 2890
An efficient and general synthesis of aziridines by the reaction of imines derived from p- toluenesulfonamides with in situ generated iodomethyllithium, with a simple and rapid experimental protocol, is reported for the first time. The reaction with the chiral aldimine