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Organic letters

Addition Reactions of Iodomethyllithium to Imines. A Direct and Efficient Synthesis of Aziridines and Enantiopure Amino Aziridines

JM Concellón, H Rodríguez-Solla, C Simal

文献索引:Barluenga, Jose; Llavona, Lujan; Yus, Miguel; Concellon, Jose M. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1991 , # 11 p. 2890

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被引用次数: 39

摘要

An efficient and general synthesis of aziridines by the reaction of imines derived from p- toluenesulfonamides with in situ generated iodomethyllithium, with a simple and rapid experimental protocol, is reported for the first time. The reaction with the chiral aldimine