Reduction of benzylic alcohols and α-hydroxycarbonyl compounds by hydriodic acid in a biphasic reaction medium

M Dobmeier, JM Herrmann, D Lenoir…

文献索引：Dobmeier, Michael; Herrmann, Josef M.; Lenoir, Dieter; Koenig, Burkhard Beilstein Journal of Organic Chemistry, 2012 , vol. 8, p. 330 - 336

全文：HTML全文

被引用次数: 15

摘要

Abstract The synthetic protocol for the reduction of alcohols to hydrocarbons by using hydriodic acid, first described by Kiliani more than 140 years ago, was improved to be more applicable to organic synthesis. Instead of a strongly acidic, aqueous solution, a biphasic toluene–water reaction medium was used, which allowed the conversion of primary, secondary and tertiary benzylic alcohols, in good yields and short reaction times, into the ...