Synthesis and antifungal activity of terpenyl-1, 4-naphthoquinone and 1, 4-anthracenedione derivatives

…, AC Mesa-Arango, L Betancur-Galvis…

文献索引：Castro, Ma Angeles; Gamito, Ana Ma; Tangarife-Castano, Veronica; Zapata, Bibiana; Miguel Del Corral, Jose Ma; Mesa-Arango, Ana C.; Betancur-Galvis, Liliana; San Feliciano, Arturo European Journal of Medicinal Chemistry, 2013 , vol. 67, p. 19 - 27

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被引用次数: 11

摘要

Abstract The antifungal evaluation of twenty seven simple and heterocycle-fused prenyl-1, 4- naphthoquinones and 1, 4-anthracenediones was performed in vitro against human pathogenic yeasts (Candida spp.) and filamentous fungi (Aspergillus spp., Fusarium spp., and Trichophyton spp.). The synthetic strategy used to obtain the quinone derivatives was initially based on the Diels–Alder cycloaddition between myrcene and several p- ...