Acta Chem. Scand.

Zeolites as catalysts in the Fischer indole synthesis. Enhanced regioselectivity for unsymmetrical ketone substrates

MP Prochazka, L Eklund, R Carlson

文献索引：Prochazka, Michal P.; Eklund, Lars; Carlson, Rolf Acta Chemica Scandinavica, 1990 , vol. 44, # 6 p. 610 - 613

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被引用次数: 22

摘要

The use of zeolites as catalysts in the Fischer indole synthesis has been studied on five unsymmetrical ketone substrates with 14 different zeolites. Both the corresponding phenylhydrazone and the parent ketone in the presence of phenylhydrazine were used as substrates. Zeolites which catalysed the indolization of the phenylhydrazones were also active in the direct conversion of the parent ketone. For substrates which gave mixtures of ...