The Fischer indole synthesis using polymer-bound hydrazines is employed as the key step for the development of a traceless indole synthesis on a solid support. ... We now report on the development of a traceless 5 solid phase indole synthesis employing the Fischer indole synthesis 6 as the key step. In planning the synthesis we envisioned generating hydrazines 2 on a solid support and treating them with appropriate ketones under typical conditions of the Fischer indole ...
