Design, synthesis, and biological evaluation of new 4-thiazolidinone derivatives substituted with benzimidazole ring as potential chemotherapeutic agents
GN Masoud, AM Youssef, MMA Khalek…
文献索引：Masoud, Georgina N.; Youssef, Amal M.; Abdel Khalek, Magdy M.; Abdel Wahab, Abeer E.; Labouta, Ibrahim M.; Hazzaa, Aly A. B. Medicinal Chemistry Research, 2013 , vol. 22, # 2 p. 707 - 725
Abstract In search of novel antiviral and anticancer agents with promising pharmacotoxicological profile, a study was initiated to synthesize new 2-thioxo-4- thiazolidinones as well as 2-phenylimino-4-thiazolidinones substituted with benzimidazole ring system. The compounds were screened primarily for their antiviral as well as anticancer activities. The synthesis of some novel 5-substituted thiazolidinones was also described. ...
