The search for clinically effective inhibitors of monoamine oxidase [amine: oxygen oxidoreductase (deaminating, flavin-containing); EC 1.4. 3.4; MA01 has been one of the continuing themes of drug research for the past 3 decades.'While the therapeutic advantages of MA0 inhibitors are generally well accepted, 2 one problem that has not yet been satisfactorily resolved is the so-called “cheese effe~ t”.~ An attractive approach to the ...
