Rearrangement of α-amino cyclopropanone hydrate: a novel route to labeled amino acids

…, A Valleix, B Rousseau, C Mioskowski

文献索引：Felpin; Doris; Wagner; Valleix; Rousseau; Mioskowski Journal of Organic Chemistry, 2001 , vol. 66, # 1 p. 305 - 308

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被引用次数: 15

摘要

Amino acids specifically labeled with stable isotopes are valuable tools for the investigation of proteins at the atomic level. Indeed, the combination of stable isotope labeling and multidimensional NMR spectroscopy is a highly efficient method for the structural study of proteins and peptides in solution. 1 Furthermore, labeled amino acids are of prime importance in the elucidation of many enzyme mechanisms. 2 The classical methods for ...