Potential noncataleptic neuroleptic agents: 2, 4-Dichloro-and 2, 4, 8-trichloro-10-piperazino-10, 11-dihydrodibenzo [b, f] thiepins

V Valenta, A Dlabač, M Protiva

文献索引：Valenta; Dlabac; Protiva Collection of Czechoslovak Chemical Communications, 1981 , vol. 46, # 3 p. 781 - 791

全文：HTML全文

被引用次数: 8

摘要

Abstract 3, 5-Dichloro-2-iodobenzoic acid (IV), prepared from 3, 5-dichloroanthranilic acid (III), was transformed in 5 steps into the diphenyl sulfide-2-acetic acids IXab. Cyclization resulted in ketones XVab which were processed in further 3 steps into the title compounds Iab and IIa. These products are mild tranquilizers devoid of cataleptic and antiapomorphine activity.