Versuche zur Synthese von Calicen aus trisubstituierten Cyclopropanen und Cyclopentenon

…, R Galli, G Sabbioni, U Stämpfli, S Walther…

文献索引：Weber, Andreas; Galli, Roberto; Sabbioni, Gabriele; Staempfli, Urs; Walter, Stefan; Neuenschwander, Markus Helvetica Chimica Acta, 1989 , vol. 72, p. 41 - 50

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被引用次数: 5

摘要

The Li carbenoids 4, prepared by treatment of substituted 1, l-dihalocyclopropanes with BuLi, are reacted with cyclopent-2-enone under thermodynamic and kinetic control (Scheme 1). In general, the latter procedure gives better yields of cyclopropylcyclopentenols 5a+, but the reaction seems to be controlled mainly by the steric and electronic properties of the substituent Y. So, with 4b and 4e, the main reaction is the attack of the carbenoid at C (1) ...