Copper toxicity has been attributed to its potential as a catalyst for oxidative damage to tissues through redox cycling between Cu (I) and Cu (II), particularly in the presence of H2O2, a by-product of oxygen metabolism. In this study, the reactions of nanomolar concentrations of Cu (I) and Cu (II) with H2O2 have been investigated in 2.0 mM NaHCO3 and 0.7 M NaCl at pH 8.0. Measurements of both the formation of the hydroxylated ...
