Abstract New investigation of Vilsmeier-type reaction was evaluated to realize the solvent effect by using pyrazolones to react with various of amides, including formamide, N- methylformamide, N-propylformamide, N-tert-butylformamide, N, N-dimethylformamide (DMF), N, N-diethylformamide (DEF), N, N-dipropylformamide (DPF), N, N- diisopropylformamide, N, N-dibutylformamide, piperidine-1-carbaldehyde, and pyrrolidine ...