Organic letters

Highly Regio-and Stereoselective Intramolecular 1, 3-Dipolar Cycloadditions of Norbornadiene-Tethered Nitrile Oxides

C Yip, S Handerson, R Jordan, W Tam

文献索引：Yip, Carol; Handerson, Sean; Jordan, Robert; Tam, William Organic Letters, 1999 , vol. 1, # 5 p. 791 - 794

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被引用次数: 32

摘要

Intramolecular cycloadditions with high regio-and stereocontrol are important methods for the efficient assembly of complex molecular structures. Efficient routes to the synthesis of norbornadiene-tethered nitrile oxides have been developed, and their intramolecular 1, 3- dipolar cycloadditions were studied. The cycloadditions occurred in good yields for a variety of substrates and were found to be highly regio-and stereoselective.