Catalytic Use of Zinc Amide for Transmetalation with Allylboronates: General and Efficient Catalytic Allylation of Carbonyl Compounds, Imines, and Hydrazones

…, T Sato, Y Yamashita, S Kobayashi

文献索引：Cui, Yi; Li, Wei; Sato, Takehiro; Yamashita, Yasuhiro; Kobayashi, Shu Advanced Synthesis and Catalysis, 2013 , vol. 355, # 6 p. 1193 - 1205

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被引用次数: 15

摘要

Abstract The efficient catalytic allylation of ketones, imines, and hydrazones with allylboronates using a catalytic amount of zinc amide is reported. In this reaction, the boron- to-zinc exchange process occurred smoothly to afford the corresponding allylzinc amides, and the desired allylation reactions proceeded in high efficiency (∼ 0.1 mol%). A mechanistic study revealed that transmetalation was a rate-determining step in the ...