During the course of ongoing studies towards the total asymmetric synthesis of Amaryllidaceae alkaloids viaretro-Cope elimination, 1 we required an efficient preparation of (4R,5S,6S)-γ-hydroxy enone 3. Hudlicky and others have shown that this enone is a versatile intermediate for the syntheses of various cyclitols, conduritols and related compounds. 2,3 It is generally prepared from enantiomerically pure cis-diol 1 (a commercially available Pseudomonas putida oxidation product of ...
![6,7-dioxabicyclo[3.2.2]nona-3,8-diene结构式](https://image.chemsrc.com/caspic/305/67963-09-1.png)