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Synthesis and biological activity of 5-aza-ellipticine derivatives

…, M Dyba, T Kosakowska-Cholody, NI Tarasova…

文献索引:Moody, Deborah L.; Dyba, Marcin; Kosakowska-Cholody, Teresa; Tarasova, Nadya I.; Michejda, Christopher J. Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 8 p. 2380 - 2384

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被引用次数: 17

摘要

Novel 5-aza-ellipticine derivatives were synthesized and tested as antitumor agents. The new compounds were prepared more readily than the analogous ellipticine derivatives, which are known to be potent anti-tumor agents Although the novel 5-aza-ellipticine derivatives are not as biologically active as their corresponding ellipticine analogues, the new compounds represent a new, readily accessible class of heteroaromatic catalytic ...