The Journal of organic chemistry

A General Strategy for the Synthesis of Vincamajine-Related Indole Alkaloids: Stereocontrolled Total Synthesis of (+)-Dehydrovoachalotine,(-)-Vincamajinine, and (-)- …

J Yu, XZ Wearing, JM Cook

文献索引：Campos, Olivia; DiPierro, Mike; Cain, Michael; Mantei, Robert; Gawish, Ali; Cook, James M. Heterocycles, 1980 , vol. 14, # 7 p. 975 - 984

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被引用次数: 57

摘要

The highly convergent stereocontrolled total synthesis of (-)-vincamajinine (7),(-)-11- methoxy-17-epivincamajine (9), and the oxygen-bridged (+)-dehydrovoachalotine (22) are described. Key steps in the synthesis of 7 and 9 involved the stereospecific enolate-driven